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...ibed the [[syndrome]] in 1866. The disorder was identified as a chromosome 21 trisomy by [[Jérôme Lejeune]] in 1959. The condition is characterized by ...ldren's Heart Institute > Heart-Related Syndromes - Down Syndrome (Trisomy 21)] Revised 8/09</ref> A [[ventricular septal defect]] is the most common for

.... <ref name=21century>[http://www.21centurycommunications.com/# 21 Century Communications]</ref> [[Category:21 Century Communications]]